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Has the Delta variant changed the symptoms of COVID-19?

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It has been said many times that the arrival of the Delta variant of the coronavirus has changed the course of the pandemic. It is more transmissible than previous variants and has quickly become the dominant variant across the world. And because the vaccines are less effective against it, although still effective enough, it has brought the need for booster shots to the forefront of the debate.

A new study has shown that the symptoms that the infection presents have also changed. According to the World Health Organization, the most common symptoms of COVID are:

1.     A new or persistent cough

2.     A fever or raised temperature

3.     A loss in the sense of smell or taste

4.     Tiredness

But results from the Zoe COVID Symptom study which monitors the symptoms of millions of people who test positive for the virus in the UK, both who are fully vaccinated and those who are unvaccinated, shows that for those who are fully vaccinated the top five symptoms are:

1.     Headache

2.     Runny Nose

3.     Sneezing

4.     Sore throat

5.     Loss of smell

For those who are unvaccinated, the top five symptoms are:

1.     Headache

2.     Sore throat

3.     Runny nose

4.     Fever

5.     Persistent cough

If we are to continue to test and isolate individuals and their contacts who potentially have COVID to help manage its spread, it is important that we recognise the wide-ranging symptoms it can present so more people know when to put themselves forward for testing. At a time where real-world data has never been more accessible and acting on it is never more urgent, it is key that countries recognise this and broaden their testing criteria.

Progress Report: Why are COVID vaccines dividing us?

We live in a world where everyone has an opinion, which can be instantly shared with millions of people across the world via social media. This can be a good thing when getting factual information out: We have seen how important it is to share personal stories from those living in areas of conflict so people can have an insider’s view of what it is like on the ground. Most recently, this has shone an important light on the plight of women in Afghanistan. However, at the same time, social media can be used to spread stories that contain inaccuracies and in the case of the COVID-19 vaccines, misinformation.

Vaccines have never been as divisive a topic as they are today.

Being vital medicines, vaccines have saved the lives of millions of people around the world since their inception and have been responsible for the eradication of diseases such as smallpox and a massive reduction in the incidence of polio.

The relatively new mRNA technology that is being used in some of the COVID-19 vaccines is now being researched in the hope it might help end other diseases like malaria. The Pfizer and Moderna vaccines are classed as mRNA vaccines, they contain a piece of genetic material that carries instructions on how to make a protein that resembles the “spike protein” on the outer surface of the coronavirus. The cells with the mRNA message make “spike proteins” and display them on their outer surface, our immune systems recognise these as foreign and prepare a short and long-term immune response. Once it has passed on its instructions, our cells break down the mRNA in a matter of days and it ceases to exist.

There has always been a minority of people who have been opposed to vaccines but the COVID-19 vaccines seem to have encouraged these people to move from the fringes of society to mainstream platforms and where before they were being ridiculed for their stance on vaccines, they are now being applauded and their voices amplified even by people who have previously been happy to take vaccines. And of course, there are those who believe the entire pandemic is a hoax and part of some wider sinister plan to reset the world order and somehow control entire populations.

This has of course angered those who have suffered first-hand as a result of the coronavirus, the healthcare workers who have been working tirelessly to care for the sick and the scientists who have escalated their efforts to come up with potential treatments and cures.

Many countries have seen public demonstrations against lockdowns and social distancing measures, as well as rallies against the use of vaccinations. Some have even seen healthcare facilities where COVID patients are being treated or where vaccines are being administered, vandalised and in some of the worst cases, healthcare professionals being abused and threatened.

[Muaz Kory/Al Jazeera]

But how did we get to this stage?

In the initial stages of the pandemic, people seemed to come together. There was a feeling of unity against an invisible virus that posed a credible threat to us all. People were supportive of healthcare workers and some countries even saw organised “claps” for those risking their lives working on the frontline. When those who were vulnerable were asked to shield and stay at home, communities came together to arrange and deliver food parcels so that they wouldn’t go without food whilst keeping safe. People seemed to understand the need for lockdowns and social distancing as offices shut down and workers were asked to stay at home. But as time went on, different groups of people had differing experiences of the pandemic. Generally, adults fell into three camps:

1.     Those who were directly affected by the illness that COVID brought, including those working on the front line.

2.     Those who were affected by only the economic consequences of the pandemic.

3.     Those who feel they are largely unaffected by the pandemic – people who ignored advice or lived in such a way the restrictions did not affect them.

This divide caused conflict. Those who were suffering economically could not balance the need for lockdowns against the large-scale financial devastation being caused by these restrictions, and those who were experiencing the real-life horrors on the front line could think of no other way to stop the deluge of sick patients presenting at hospitals. Children also suffered as school closures had a detrimental effect on education and they no longer had the opportunities for social interactions that they depend on for development, and this overwhelmed and stressed many parents.

The pandemic also divided people along socioeconomic and racial lines. It became apparent early on that those who were living in poorer socioeconomic areas were most likely to become sick from the virus. A chronic lack of investment in these communities forced them to live in overcrowded housing. Combined with an already increased risk of other health conditions due to poverty, this put them at higher risk of dying from the virus.

It was the same for those from minority backgrounds. They too were more likely to live in poorer neighbourhoods, work in jobs they could not do from home and many also had pre-existing health conditions that increased their risk of getting seriously sick from the virus.

As time went on, the economic damage deepened, and for those whose livelihoods were at risk, the idea of protecting the vulnerable at their expense began to wear thin. The goodwill offered to front-line workers also started to fade, with people voicing their opposition to how healthcare workers were being lauded in public forums; they began to see them as a symbol of lockdowns and restrictions.

Then came the vaccines.

Initially, the reception was positive. We finally had a tool that could potentially herald the beginning of the end of the pandemic. People were hopeful. But anti-vaxxers soon jumped online and began to spread misinformation about them in an attempt to thwart the vaccination effort.

It did not help that the early messaging about the vaccines was unclear, although it later changed as more evidence emerged, including information around their safety during pregnancy and whether or not they could be given to women trying to conceive. It is now clear that on balance, it is safer for pregnant women to take the vaccines than risk getting COVID and also that the vaccines have no effect on fertility. Despite this, misinformation about the vaccines causing infertility persists.

People who are against the vaccines have been especially vocal, and anti-vaxxers have seen their support and numbers grow. This appears to have worsened as governments start to vaccinate younger age groups. A recent rally in London saw people opposed to the vaccination of children bombarding healthcare professionals with neo-Nazi slurs and telling them they were going to be hanged like the doctors and nurses in the Nuremberg trials. This caused immense distress amongst healthcare professionals who have been risking their own lives looking after others throughout the pandemic.

We must not ignore the part that news outlets have played in encouraging this divide throughout the pandemic. News channels now tend to rely on clickbait online articles and heated television debates to reel viewers in. This has meant more and more controversial voices have been given platforms on major media outlets, both on television and in print, for the simple reason that they benefit news corporations. They may dress it up as presenting “both sides of an argument”, but when one side is not based on evidence and relies only on the opinion of an unqualified individual, they are only serving to spread further misinformation. These heated debates and opinion pieces have sowed the seeds of doubt in many people’s minds when it comes to the vaccines, potentially leading to the deaths of some of those who got COVID after choosing not to get vaccinated because they were influenced by the misinformation they saw online or on television.

There is no doubt that the pandemic has divided us in more ways than one. It will take time to heal and will require leadership from those in charge. There are individuals, big organisations and even whole countries who stand to benefit by deepening these divides. Whether or not they will succeed remains to be seen, but this doctor feels there is more to be gained from coming together than being pulled further apart.

Good News: Long COVID in children less common than originally thought

A group of researchers led by University College London have concluded that the risk of Long COVID in children is much lower than previously feared. They surveyed more than 50,000 children aged between 11 and 17 who had tested positive for coronavirus in England between September 2020 and March 2021. According to their results, between 2 percent and 14 percent of these children still had symptoms 15 weeks after their initial infection, but few had continuing symptoms that required them to seek medical help or take significant time off school.

[Muaz Kory/Al Jazeera]

Initial studies carried out in Rome, that interviewed 129 children aged between six and 16 from March to November 2020, reported that more than a third had one or two lingering symptoms after four months. So these latest findings, although still worrying, will reassure parents that if their child was to catch the virus, there is less risk than originally thought of them going on to develop Long COVID.

But the risk of Long COVID, although smaller, does still exist and the authors of the study are anxious to point out that the numbers were still not trivial and the illness needed to be taken seriously in children.

It is clear from this study that children are not “immune” from the effects of this virus, a narrative that many continue to pedal, but it is welcome news that they may be less susceptible to Long COVID than originally thought.

In the Doctor’s Surgery: How the pandemic is affecting the mental health of my patients

Mental health has been an ongoing concern throughout the pandemic. Initially, I was seeing patients who were so worried about contracting the virus that they began to show symptoms of anxiety and altered mood. I also saw an exacerbation of symptoms in those living with obsessive-compulsive disorder (OCD) as the continuing messaging around hygiene and cleaning surfaces had detrimental effects on their mental health and many of them had to seek medical attention.

More recently, I am seeing the longer-term effects of the pandemic on my patients’ mental health.  Some have lost loved ones and are now suffering symptoms of depression that go beyond those expected from a bereavement reaction. There are young people suffering anxiety at the thought of going back to school and university. There are people who have suffered financial hardship as a consequence of multiple lockdowns whose mental health has deteriorated. It can be difficult listening to all these personal stories of hardship all day, but however hard it is for me, it is much harder for them.

Mental health problems can strike any one of us at any point in our lives. It is important to recognise the symptoms and seek help. There are many symptoms of anxiety and depression, both physical and mental, but the most common ones are:

·       Continuously feeling sad or low in mood

·       Feeling hopeless or getting tearful

·       Having no motivation or interest in things you used to enjoy

·       Getting no enjoyment out of life

·       Constantly being on edge or having a continuing sense of dread

For some people, their anxiety or depression may get so severe they have thoughts of harming themselves.

Physical symptoms can include tiredness, palpitations, dizziness and breathlessness.

Whatever your symptoms, it is important you talk to someone about them, preferably a medical professional. There are lots of treatment options available and the experts will work with you to decide what is best for you. This can take the form of talking therapy, social prescribing – eg exercise and nature on prescription, or medication, or it may be a combination of these things. It is important to think about mental health in the same way you think about physical health: Take it seriously and do things every day to keep your mind healthy. Taking daily exercise, spending time in green spaces and talking about how you are feeling have all been proven to help with poor mental health. Don’t downplay your symptoms – they are important and healthcare professionals will take you seriously if you open up to them.

I have lost patients to mental health conditions and passionately advocate for those suffering from poor mental health. Please do not suffer in silence.

Reader’s Question: Do vaccines help prevent Long COVID?

Answer: Yes.

A study carried out by Kings College London has shown that being fully vaccinated cuts the odds of symptoms lasting longer than four weeks by 50 percent.

Long COVID is identified when symptoms persist for four weeks or more following the initial COVID infection. The study looked at nearly a million people who were fully vaccinated and only 592 went on to test positive for COVID. Of these 592, only 31, which is 5 percent of the cohort, reported symptoms four weeks or more after infection. In the unvaccinated group, this figure was 11 percent. This is another reason to take the vaccine when offered it.



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